METHOD FOR DETERMINING PROBABILITY OF UNFAVOURABLE OUTCOME IN PATIENT WITH TUBERCULOSIS ASSOCIATED WITH HIV INFECTION IN ADMISSION IN HOSPITAL OF FEDERAL PENITENTIARY SERVICE OF RUSSIA FOR FOUR CLINICAL SIGNS Russian patent published in 2020 - IPC A61B5/00 

Abstract RU 2738211 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to phthisiology, and can be used for determining the probability of an unfavourable outcome in a patient suffering from tuberculosis associated with HIV infection, when admitted to a hospital of the Federal Penitentiary Service of the Russian Federation. Patient is diagnosed with the following symptoms: dyspnoea (D) complaints, weight loss (L), presence of splenomegaly (S), fever (F), wherein in the presence of a feature, value of 1 is assigned to it, and in the absence of a value, value of 0 is given, followed by calculation using a formula. Each feature is given an experimentally determined weight value in the form of a product of constant coefficient or 1, or 0, depending on presence or absence of the attribute: (1.40486) and if dyspnoea (D) = 1, absent = 0; (1.74790) and in the presence of weight loss (L) = 1, absence = 0; (1.68617) and in the presence of splenomegaly (S) = 1, absence = 0; (1.91843) and in the presence of fever (F) = 1, absence = 0; and is summed with constant equal to (-5.35489) with subsequent calculation by formula

where e is the base of the natural logarithm = 2.71828947, z is the sum of the numerical values of each of the features, z = (-5.3489) + 1.40486 × (D) + 1.74790 × (L) + 1.68617 × (S) + 1.1843 × (F), where "D" - presence of dyspnoea, "L" - presence of weight loss, "S" - presence of splenomegaly, "F" - presence of fever. Derived probability is used to conclude that it is advisable to continue monitoring and treating a patient suffering from tuberculosis associated with HIV infection when admitted to a hospital of the Federal Penitentiary Service of the Russian Federation in the intensive care ward. If probability is 50 % or more, the risk of the unfavourable outcome and the need to hospitalize the patient in the intensive care unit are predicted, if the probability is less than 50 %, the patient is hospitalized in a hospital ward.

EFFECT: method provides detecting a possible adverse outcome of the disease by a limited number of clinical manifestations.

1 cl, 1 dwg, 2 tbl

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RU 2 738 211 C1

Authors

Borovitskij Vladislav Semenovich

Razin Maksim Petrovich

Dates

2020-12-09Published

2019-11-21Filed