FIELD: pharmaceutical industry.
SUBSTANCE: invention relates to a soft gelatine capsule. Soft gelatine capsule containing shell and filler, wherein the filler contains a dispersed or solubilized active ingredient and gelatin having jellification capacity and Bloom strength in range of 60 to 150, hydrolysed gelatine, 85 % glycerine, water, pectin and gellan gum taken in a certain ratio, and the shell contains gelatin having Bloom strength in range of 110 to 300, anhydrous glycerin as a plasticiser, water, taken in certain amount.
EFFECT: above described shell provides gradual release of active ingredient regardless of pH.
5 cl, 4 dwg, 2 tbl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
SUSTAINED RELEASE SOFT GELATINE CAPSULES | 2020 |
|
RU2822392C2 |
SOLID OR SEMI-LIQUID TIME-RELEASE DOSAGE FORMS | 2008 |
|
RU2471480C2 |
SMOKING DEVICE WITH FRAGILE CAPSULE, FRAGILE CAPSULE AND ITS PRODUCTION METHOD | 2006 |
|
RU2415618C2 |
CONTROLLED SUPERFICIAL GEL-GENERATION OF MUCOADHESIVE POLYMERS IN ORAL CAVITY MUCOSA | 2008 |
|
RU2440809C2 |
GELLAN SEAMLESS, ABLE FOR MECHANICAL DESTRUCTION CAPSULE AND METHOD OF OBTAINING IT | 2006 |
|
RU2428971C2 |
PHARMACEUTICAL SOFT GELATIN CAPSULE DOSAGE FORM WITH MODIFIED GUAR GUM | 2014 |
|
RU2676480C2 |
CONFECTIONARY PRODUCT CONTAINED IN CASING AND METHOD OF ITS OBTAINING | 2006 |
|
RU2396000C2 |
METHOD FOR SOLUBILIZATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE | 2019 |
|
RU2787999C2 |
FOOD PRODUCT WHICH REDUCES CONTENT OF SERUM CHOLESTEROL | 2015 |
|
RU2726453C2 |
FAST DISPERSING GELATIN-COATED TABLETS | 2005 |
|
RU2367413C2 |
Authors
Dates
2020-12-18—Published
2016-11-25—Filed