IMMUNOGLOBULIN REMOVING SORBENT Russian patent published in 2008 - IPC A61K35/16 A61K39/395 A61K39/44 A61M1/36 

Abstract RU 2325172 C2

FIELD: medicine; immunology.

SUBSTANCE: sorbent is offered to remove immunoglobulin from human blood plasma. This sorbent contains agarous matrix covalently combined with ligand. As a ligand at that it contains F(ab)2 fragments of specific affinely-purified polyclonal antibodies blocking human immunoglobulin G. Sorbent is actually biologically inert, biocompatible agarous matrix. Sorbent is characterized with higher sorptive capacity and safety of immunosorbents used practical purposes, specifically for therapeutic aphaeresis in comparison to well-known polyclonal bodies based sorbents.

EFFECT: considerable reduction of prospective immunological response of human body for foreign protein.

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Authors

Pokrovskij Sergej Nikolaevich

Dmitrieva Oksana Aleksandrovna

Afanas'Eva Ol'Ga Il'Inichna

Altynova Elena Vladimirovna

Kipor Svetlana Gennadievna

Dates

2008-05-27Published

2006-07-24Filed