FIELD: medicine.
SUBSTANCE: invention refers to molecular oncology. Disclosed is a minimally invasive method for detecting rectal tumour sensitivity to radiation therapy based on variation of duplicity of H2AX genes and RBBP8 relative to the reference GAPDH gene by PCR-PB in the presence of EVA-Green dye and high-specific primers.
EFFECT: method has high sensitivity and specificity, enables making the diagnosis procedure more simple and accurate, and also enables timely correction of the therapeutic approach.
1 cl, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| MINIMALLY INVASIVE METHOD FOR DETECTING SENSITIVITY OF PROSTATE TUMOURS TO RADIATION THERAPY BASED ON CHANGE IN BRCA2 AND RAD50 GENE COPYING | 2019 |
|
RU2728428C1 |
| MINIMALLY INVASIVE METHOD FOR DIAGNOSIS OF HIGH-GRADE SEROUS OVARIAN ADENOCARCINOMA BASED ON COPY INDEX OF SULT1E1, CYP1B1, AND ESR1 GENES | 2021 |
|
RU2750472C1 |
| METHOD FOR DETERMINING THE RADIOSENSITIVITY OF MALIGNANT RECTAL TUMOURS | 2020 |
|
RU2754154C1 |
| METHOD FOR DIFFERENTIAL DIAGNOSIS OF SQUAMOUS CELL CARCINOMA OF TONGUE AND BENIGN NEOPLASM OF TONGUE | 2024 |
|
RU2841122C1 |
| MINIMALLY INVASIVE METHOD FOR DIFFERENTIAL EARLY DIAGNOSIS OF HEPATOCELLULAR CARCINOMA AND FATTY HEPATOSIS | 2023 |
|
RU2822224C1 |
| MINIMALLY INVASIVE METHOD FOR DIAGNOSTICS OF LUNG CANCER ON BASIS OF CHANGING COPY NUMBER OF MTDNA HV2 LOCUS | 2018 |
|
RU2678227C1 |
| METHOD FOR NON-CONTACT STIMULATION OF TRANSCRIPTIONAL ACTIVITY OF CYCLIN-DEPENDENT KINASE 2 INHIBITOR GENE IN PROSTATE TUMOR CELLS | 2020 |
|
RU2763992C1 |
| MINIMALLY INVASIVE METHOD FOR DIAGNOSING METASTATIC LESIONS OF REGIONAL LYMPH NODES IN PATIENTS WITH CERVICAL CANCER BASED ON THE COPY NUMBER OF THE CCND1 AND PPARGC1A GENES | 2021 |
|
RU2766774C1 |
| METHOD FOR PREDICTION OF METASTASES DEVELOPMENT IN PATIENTS WITH GASTRIC CANCER | 2016 |
|
RU2624505C1 |
| METHOD OF EXTRACTING EXTRACELLULAR DEOXYRIBONUCLEIC ACID FROM BLOOD | 2008 |
|
RU2372405C1 |
