FIELD: medicine.
SUBSTANCE: group of inventions relates to treatment of skin diseases. Method of treating acne in a subject in need thereof comprises administering to a subject a composition comprising a substituted or unsubstituted diindolylmethane, where the composition is administered by a sublingual or buccal pathway. Also disclosed is a method of treating rosacea in a subject in need thereof.
EFFECT: group of inventions provides improved bioavailability and pharmacokinetic parameters of substituted or unsubstituted diindolylmethane after sublingual or buccal administration compared to oral administration.
30 cl, 2 tbl, 7 ex, 2 dwg
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