ANTIBODY WHICH BINDS A LINEAR EPITOPE OF HUMAN P53, AND USE THEREOF IN DIAGNOSIS Russian patent published in 2021 - IPC C07K16/32 G01N33/50 

Abstract RU 2741795 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to an antibody which specifically binds to a human p53 protein. Also disclosed is a method of producing said antibody, a method of in vitro determining the isoform of human protein p53, to which said antibody binds, method for in vitro diagnosis of Alzheimer's disease and an in vitro method for determining predisposition of a subject suffering a slight cognitive disorder to developing Alzheimer's disease with said antibody. Disclosed is an immunoassay kit comprising said antibody.

EFFECT: invention enables effective treatment of Alzheimer's disease associated with p53 protein.

10 cl, 5 ex, 5 dwg

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RU 2 741 795 C2

Authors

Memo Maurizio

Uberti Daniela Letizia

Dates

2021-01-28Published

2015-09-25Filed