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(19)

RU

(11)

2 742 305

(13)

C2

(51)

IPC

C07D471/04(2006-01-01)

A61K31/437(2006-01-01)

A61K31/4375(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2017126995, 2015-12-30

(24)

Start date

2015-12-30

(22)

Actual filing date

2015-12-30

(45)

Published

2021-02-04

(72)

Inventor

Hartman, George, D.Kuduk, Scott

(73)

Holder

Novira Therapeutics, Inc.

DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS Russian patent published in 2021 - IPC C07D471/04 A61K31/437 A61K31/4375 A61P31/12 

Abstract RU 2742305 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound of formula III, in which Y denotes -C(O); R1 is C6 aryl, thiophenyl, thiazolyl; R2 in each case is independently selected from H and C1-C6 alkyl, with the proviso that at least one of R2 is C1-C6 alkyl; R3 is selected from H; R4 is selected from

; and R7 is selected from H, C1-C6 alkyl. Invention also relates to individual compounds, to a pharmaceutical composition and to use of a pharmaceutical composition.

EFFECT: obtaining novel compounds of formula III, which can be used for treating hepatitis B virus infection.

5 cl, 3 tbl, 64 ex

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RU 2 742 305 C2

Authors

Hartman, George, D.

Kuduk, Scott

Dates

2021-02-04—Published

2015-12-30—Filed

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