METHOD FOR RAPID ASSESSMENT OF CHANGES IN LUNG TISSUE WITH COVID-19 WITHOUT USING COMPUTER TOMOGRAPHY OF THORAX ORGANS Russian patent published in 2021 - IPC A61B5/00 G01N33/50 

FIELD: medicine.
SUBSTANCE: invention relates to medicine, in particular to pulmonology and therapy, and can be used for the rapid assessment of the condition in patients with COVID-19, which makes it possible, inter alia, to determine the necessity of hospitalization of a patient in a hospital. The method for the rapid assessment of changes in lung tissue with COVID-19 involves determining a set of diagnostically significant indicators, for which purpose the level of biomarkers in the sample of biological fluids, blood and urine, obtained in the subject is measured; physical examination; collection of anamnesis, obtaining data on diagnostically significant indicators: severity of the patient’s condition, respiratory rate, respiratory or respiratory difficulties, body temperature, presence of a sense of insensitivity in the thorax, weakness and/or a sense of bone ache, cough, type of cough, sex, age of test, ischaemic heart disease, risk group: chronic disease, and/or pregnancy, and/or age 65 and over, as well as quantitative SARS-CoV-2 antibodies IgG and IgM, C-reactive protein, absolute number of lymphocytes, absolute number of granulocytes, absolute number of normablasts, ESR under Westergren, hematocrit, p24 HIV-1 antigen and/or antibody HIV-1/2, urobilinogens, nitrites; all the data obtained are processed using at least one classification model, which has been trained to determine the absence of lesions of pulmonary tissue, light, medium-heavy or severe pulmonary tissue.

EFFECT: technical result achieved when using the developed method is possibility of rapidly assessing degree of change of lung tissue with COVID-19 without using instrumental methods of investigation.
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