FIELD: biotechnology.
SUBSTANCE: present invention refers to recombinant human growth hormone (hGH), and can be used in medicine. Invention enables to obtain a glycosylated form of somatotropin (hGH), modified with CTP-extension segments and having increased half-life, as well as high stability in comparison with known analogues.
EFFECT: invention can be used in therapy of diseases associated with growth hormone deficiency or disturbed secretion in a subject.
21 cl, 24 dwg, 3 ex, 3 tbl
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