MILD DOSAGE FORM FOR TREATING ONCOLOGICAL DISEASES Russian patent published in 2021 - IPC A61K31/505 A61P35/00 A61K47/10 

Abstract RU 2743342 C1

FIELD: medicine.

SUBSTANCE: present invention refers to medicine, namely to a soft dosage form for treating oncological diseases, comprising fluorouracil as an active substance, characterized by that for treating skin cancer, the active substance contains iron-based Fe3O4 nanoparticles, and the water-soluble base used is a mixture of polyethylene glycols with molecular weights of 400 and 1000, with the following ratio of components: 5-fluorouracil - 5 g, Fe3O4 nanoparticles - 0.100 g, PEG 400 - 59.13 g, PEG 1000 - 24.4 g, sodium hydroxide - 1.37 g, water - 10 ml.

EFFECT: present invention provides higher clinical effectiveness ensured by improved penetration of active substances into the area of damaged skin and its edges.

1 cl, 2 dwg, 3 tbl

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RU 2 743 342 C1

Authors

Melnikova Olga Aleksandrovna

Melnikov Mikhail Yurevich

Minin Artem Sergeevich

Ermakov Anatolij Egorovich

Melnikov Aleksandr Mikhajlovich

Dates

2021-02-17Published

2020-06-29Filed