FIELD: medicine.
SUBSTANCE: present invention refers to medicine, namely to a soft dosage form for treating oncological diseases, comprising fluorouracil as an active substance, characterized by that for treating skin cancer, the active substance contains iron-based Fe3O4 nanoparticles, and the water-soluble base used is a mixture of polyethylene glycols with molecular weights of 400 and 1000, with the following ratio of components: 5-fluorouracil - 5 g, Fe3O4 nanoparticles - 0.100 g, PEG 400 - 59.13 g, PEG 1000 - 24.4 g, sodium hydroxide - 1.37 g, water - 10 ml.
EFFECT: present invention provides higher clinical effectiveness ensured by improved penetration of active substances into the area of damaged skin and its edges.
1 cl, 2 dwg, 3 tbl
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Authors
Dates
2021-02-17—Published
2020-06-29—Filed