INTEGRATED THERAPY OF STOMACH CANCER Russian patent published in 2009 - IPC A61K31/513 A61K31/7048 A61K31/542 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention concerns medicine, namely oncology, and can be used for integrated therapy of stomach cancer. The therapy involves surgical procedure and pharmacotherapy. For 3-7^th postoperative day, removal of drainages is immediately followed with endolymphatic infusion with single-stage introduction of 5-fluorouracil 750 mg, etoposide 100 mg and ceftriaxon 3.0 g in total amount up to 20 ml. The procedure is performed every 7 days.

EFFECT: application of the invention provides prevention of local recurrence of stomach cancer in the early postoperative period ensured by action on subclinical micrometastases in lymphatic channels, reduces risk of postoperative pancreatitis due to inhibitory action of 5-fluorouracil on pancreatic secretion and rate of postoperative intra-abdominal inflammatory processes owing to ensured great concentration of antibacterial preparations in abdominal cavity.

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