Pharmaceutical composition based on tramadol for ophthalmic use Russian patent published in 2021 - IPC A61K31/135 A61K47/02 A61K47/36 A61K47/38 A61K9/08 A61P27/02 

FIELD: pharmaceuticals.

SUBSTANCE: group of inventions relates to the field of pharmaceuticals, namely to an aqueous ophthalmic pharmaceutical composition and its use for the local treatment of eye pain. The composition contains tramadol or its pharmacologically acceptable salt as the sole active ingredient at a concentration of 0.04% wt. / vol. to 0.07% wt. /vol., expressed as an equivalent concentration of tramadol hydrochloride, an isotonant, a pH-regulating substance, and water as the carrier medium.

EFFECT: group of inventions provides a composition with very high efficacy for the local treatment of eye pain with tramadol content in the range of low concentrations of 0.04–0.07% wt. /vol. and in the absence of other active ingredients.

13 cl, 2 tbl, 2 ex