FIELD: medicine; pharmaceuticals.
SUBSTANCE: present invention relates to an aqueous pharmaceutical composition of ibuprofen and tramadol for ophthalmic use. Composition contains ibuprofen in form of a salt with arginine in concentration of 0.05–0.2 wt./vol., tramadol or its pharmaceutically acceptable salt in concentration from 0.075 to 1.5 wt./vol. and water. Molar ratio of ibuprofen and arginine ranges from 1.2:1 to 1:1.2. Composition can additionally contain sodium chloride as an isotonizing agent.
EFFECT: said composition is effective and safe in local ophthalmic application and reduces side effects.
14 cl, 3 tbl, 3 ex
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