FIELD: pharmacology.
SUBSTANCE: ophthalmic composition in the form of eye drops contains a polyaphron dispersion and has a viscosity of 1 to 50 Pa⋅S at a shear rate of 1 s-1,wherein the said composition comprises a non-ionic, non-halogenated surfactant, a pharmaceutically acceptable oil selected from the group consisting of castor oil, long chain triglycerides, medium chain triglycerides, mineral oil, silicones, phospholipids, mono- and diglycerides, and mixtures of two or more thereof, and a pharmaceutically active agent - cyclosporin, wherein the composition does not contain a fluorinated surfactant.
EFFECT: improved active agent penetration through the cornea.
14 cl, 10 ex, 1 dwg
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Authors
Dates
2017-12-21—Published
2012-03-14—Filed