FIELD: biochemistry.
SUBSTANCE: invention relates to a method for CD34+ population transduction of hematopoietic stem cells or progenitor cells, including culturing said cells in a culture medium in the presence of a lentiviral vector, an agent which enhances the transmission of prostaglandin EP receptor signals, and a poloxamer.
EFFECT: invention allows improving transduction efficiency of haematopoietic stem cells and precursor cells.
11 cl, 27 dwg, 32 ex
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Authors
Dates
2021-03-11—Published
2017-02-10—Filed