METHOD FOR STABLE CELL TRANSDUCTION BY VIRAL VECTORS Russian patent published in 2006 - IPC C12N5/00 C12N15/63 

Abstract RU 2280074 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to method for stable cell transduction of hematopoesis system or hematopoesis stem cells. Claimed method includes simultaneous cell in vivo or in vitro contact with lentivirus vector and molecule bonding to cell surface. Method of present invention allows stable transduction more 75 % of cells over 14 days. Method for introduction of gene material into cell also is disclosed.

EFFECT: new method useful in medicine, virology, and gene engineering.

40 cl, 28 dwg, 9 ex

Similar patents RU2280074C2

Title Year Author Number
PRODUCTION OF CONSTRUCTED CELLS FOR ADOPTIVE CELL THERAPY 2017
  • Beauchesne, Pascal
  • Tareen, Semih, U.
RU2780156C2
LENTIVIRAL VECTORS PSEUDOTYPED BY MUTANT BaEV GLYCOPROTEINS 2012
  • Zhirar-Ganpen Anais
  • Verkhoen El
  • Lavilet Dimitri
  • Kosse Fransua-Loik
RU2618864C2
VIRAL VECTORS WITH CONDITION-DEPENDENT REPLICATION AND THEIR USING 2001
  • Chang Jung-Nien
  • Lu Ksiaobin
  • Slepushkin Vladimir
  • Kound Betti
  • Dehvis Brajan
  • Ju Kviao
  • Jang Janping
  • Merling Rehndall
  • Khan Vej
  • Ni Jadzin
  • Li Juehksia
  • Dropulik Boro
RU2301260C2
PRODUCTS OF A CERTAIN COMPOSITION CONTAINING GENETICALLY MODIFIED T CELLS 2015
  • Dzhensen Majkl K.
RU2751921C2
METHODS OF EXPANSION OF ANTIGEN-SPECIFIC CAR-T-CELLS, COMPOSITIONS AND THEIR USE 2019
  • Aftab, Blake, T.
  • Pham, Christina
  • Shen, Rhine
  • Wu, Michelle
RU2800920C2
METHOD AND COMPOSITIONS FOR CELLULAR IMMUNOTHERAPY 2012
  • Riddell Stenli R.
  • Khudetsek Mikhael
RU2688185C2
IMPROVED METHODS FOR PRODUCING ADOPTIVE CELL THERAPY AGENTS 2015
  • Morgan Richard
  • Friedman Kevin
  • Maier Dawn
RU2741899C2
DOUBLE VECTOR FOR SUPPRESSION OF HUMAN IMMUNODEFICIENCY VIRUS 2010
  • Chen Irvin
  • Ehn Don Sunn
  • Millington Mishel'
  • Bojd Maurin
  • Sajmonds Dzheffri P.
  • Breton Luis Rehndol
RU2562868C2
RECOMBINANT LENTIVIRAL VECTOR, HOST CELL TRANSDUCED WITH LENTIVIRAL VECTOR, METHODS FOR TRANSDUCTION AND USES THEREOF 2002
  • Trono Did'E
  • Viznerovich Matsej
RU2305708C2
COMPOSITIONS INCREASING THE NUMBER OF COPIES OF THE VECTOR (VCN), AND METHODS OF USING 2017
  • Bonner, Melissa
  • Negre, Olivier
RU2744603C2

RU 2 280 074 C2

Authors

Jumo Loran

Khan Vej

Lu Ksiaobin

Slepushkin Vladimir

Lesher Mishell'

Dehvis Brajan

Chang Jung-Nien

Dropulik Boro

Dates

2006-07-20Published

2001-08-29Filed