FIELD: ophthalmology.
SUBSTANCE: invention is intended to prevent or treat visual impairment. For the prevention or treatment of visual impairment, such as macular degeneration, glaucoma or diabetic retinopathy, a composition containing the active ingredients is used: (a) ursodeoxycholic acid (UDCA) selected from ursodeoxycholic acid, taurosodeoxycholic acid and glycoursodeoxycholic acid; (b) a water-soluble starch conversion product, wherein the pH of said composition is 6.5-8. The water-soluble starch conversion product is maltodextrin. The minimum mass ratio of ursodeoxycholic acid and maltodextrin is 1: 13-1: 25. The specified composition is prepared for intravitreal injection. A single dose of UDCA for intravitreal injection is 50-100 μl at a concentration of 0.1-1.5 mg / ml.
EFFECT: use of the invention provides an excellent effect of preventing or treating visual impairment diseases such as macular degeneration, glaucoma and diabetic retinopathy.
8 cl, 24 dwg, 9 tbl, 12 ex
Authors
Dates
2021-04-16—Published
2018-02-09—Filed