COMPOSITION FOR THE PREVENTION OR TREATMENT OF VISUAL IMPAIRMENT CONTAINING URSODEOXYCHOLIC ACID Russian patent published in 2021 - IPC A61K9/08 A61K31/575 A61K31/718 A61K47/26 A61K47/36 A61P27/02 

Abstract RU 2746592 C1

FIELD: ophthalmology.

SUBSTANCE: invention is intended to prevent or treat visual impairment. For the prevention or treatment of visual impairment, such as macular degeneration, glaucoma or diabetic retinopathy, a composition containing the active ingredients is used: (a) ursodeoxycholic acid (UDCA) selected from ursodeoxycholic acid, taurosodeoxycholic acid and glycoursodeoxycholic acid; (b) a water-soluble starch conversion product, wherein the pH of said composition is 6.5-8. The water-soluble starch conversion product is maltodextrin. The minimum mass ratio of ursodeoxycholic acid and maltodextrin is 1: 13-1: 25. The specified composition is prepared for intravitreal injection. A single dose of UDCA for intravitreal injection is 50-100 μl at a concentration of 0.1-1.5 mg / ml.

EFFECT: use of the invention provides an excellent effect of preventing or treating visual impairment diseases such as macular degeneration, glaucoma and diabetic retinopathy.

8 cl, 24 dwg, 9 tbl, 12 ex

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RU 2 746 592 C1

Authors

Song Yeong Ho

Ko Hwi Jin

Dates

2021-04-16Published

2018-02-09Filed