NEW PROSTAGLANDIN DERIVATIVE Russian patent published in 2021 - IPC C07C405/00 C07H3/06 A61K31/5575 A61K47/40 A61P9/00 A61P9/08 A61P9/10 A61P9/12 

Abstract RU 2748837 C2

FIELD: chemical compounds.

SUBSTANCE: present invention relates to the compound represented by Formula (1), or to its pharmacologically acceptable salt, or to the cyclodextrin-clathrate form of the compound of Formula 1, or to its pharmacologically acceptable salt, which are used to treat a blood flow disorder, as well as to a medicinal product.

In Formula 1 R1 and R2 each independently is a hydrogen atom or an alkyl group having 1-3 carbon atoms, A-B is a carbon-carbon double bond, a hydroxy group linked by a wavy line is a hydroxy group having α-configuration, β- configuration, or a mixed configuration of α-configuration and β-configuration, n is 1, а Y, RA, R3 have the values specified in the claim, or the compound represented by Formula 1 is selected from methyl ((1R,2R,3R)-3-hydroxy-2-((1E,3RS,4S)-3-hydroxy-4-methylnone-1-en-6-in-1-yl)-5-oxocyclopentyl) heptanoate and 7-((1R, 2R,3R)-3-hydroxy-2-((1E, 3S,4S)-3-hydroxy-4-methylnone-1-en-6-in-1-yl)-5-oxocyclopentyl) heptanic acid.

EFFECT: invention is used to treat blood flow disorder.

13 cl, 4 tbl, 29 ex

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RU 2 748 837 C2

Authors

Yasuda, Arata

Matsumura, Yasusi

Savada, Kazuesi

Nanba, Khirojosi

Taguti, Kadzuki

Dates

2021-05-31Published

2017-05-09Filed