FIELD: biotechnology.
SUBSTANCE: methods for the treatment of B-cellular lymphoma are proposed. In this case, the method includes immunotherapy with genetically modified T-cells aimed at CD19 in a combination with 4-1BB agonist (CD137).
EFFECT: invention can be used for efficient treatment of B-cellular lymphoma, including diffuse large-cell B-cellular lymphoma.
47 cl, 14 dwg, 9 tbl, 5 ex
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