CONTROL POINT INHIBITOR AND WHOLE MYCOBACTERIAL CELLS FOR USE IN CANCER THERAPY Russian patent published in 2020 - IPC A61K39/395 A61P35/00

Abstract RU 2733033 C2

FIELD: medicine; oncology.

SUBSTANCE: present group of inventions refers to cancer therapy. That is ensured by using a combined therapy comprising an immunomodulator and a control point inhibitor. Immunomodulator contains a whole cell of non-pathogenic thermoinactivated Mycobacterium obuense, and the control point inhibitor is an antibody selected from pembrolizumab, atezolizumab, tremelimumab, MGA-271, AMP-224, BMS-986016.

EFFECT: this provides effective cancer treatment ensured by synergetic action of the drugs.

26 cl, 3 dwg, 2 ex

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RU 2 733 033 C2

Authors

Akle Charles

Brunet Laura Rosa

Dates

2020-09-28—Published

2016-06-24—Filed