FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular to a rodent that expresses the humanized protein Tmprss, as well as to its cell and tissue. Also disclosed is a rodent embryo to produce a rodent that expresses the humanized Tmprss protein. The invention also relates to a method for obtaining a rodent having a humanized Tmprss gene.
EFFECT: invention makes it possible to effectively evaluate the therapeutic efficacy of a compound in the treatment of influenza virus infection.
32 cl, 4 dwg, 4 tbl, 3 ex
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