PURINONE DERIVATIVE HYDROCHLORIDE Russian patent published in 2021 - IPC C07D473/18 A61K31/522 A61P29/00 A61P7/02 A61P19/00 A61P35/00 A61P37/08 A61P37/02 

Abstract RU 2750538 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a pharmaceutical composition based on 6-amino-9-[(3R)-1-(2-butinoyl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purine-8-one hydrochloride, which has the activity of a selective Btk inhibitor, useful for the prevention and/or treatment of Btk-related diseases. The invention also relates to the use of 6-amino-9-[(3R)-1-(2-butinoyl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purine-8-one hydrochloride.

EFFECT: pharmaceutical composition based on a Btk inhibitor has been obtained that is useful for the treatment of non-Hodgkin's lymphoma, autoimmune disease, and other Btk-related diseases.

6 cl, 4 dwg, 6 tbl, 15 ex

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RU 2 750 538 C2

Authors

Yamamoto Singo

Esidzava Tosio

Dates

2021-06-29Published

2012-11-28Filed