FIELD: medicine.
SUBSTANCE: invention relates to the treatment of lymphoma. The use of the therapeutically effective amount of a compound selected from N-[(1-acryloylpiperidine-4-yl)methyl]-5-(4-phenoxyphenyl)pyrimidine-4,6-diamine and 1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidine-4-yl)amino)methyl)-4-fluoropiperidine-1-yl)prop-2-en-1-one, their pharmaceutically acceptable salts, tautomers and stereoisomers, including their mixtures in all ratios, for the treatment or prevention of myeloproliferative disorders or malignant tumor is disclosed, where malignant tumor is selected from non-Hodgkin lymphoma of mantle zone cells and non-Hodgkin diffuse B-large cell lymphoma, including the abc subtype.
EFFECT: invention provides for the treatment of lymphoma without undesirable effects outside targets.
4 cl, 8 dwg, 2 tbl, 2 ex
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