FIELD: pharmacy and medicine.
SUBSTANCE: group of inventions relates to the field of pharmacy and medicine, more specifically to the oral dosage form of favipiravir and its use. The proposed dosage form of favipiravir, which exhibits preventive and/or therapeutic antiviral activity, is a film-coated tablet, including a core and a film shell. At the same time, the core of the tablet has the following composition: favipiravir 200 mg, microcrystalline cellulose 100.00-140.00 mg, low-substituted hydroxypropyl cellulose 50.00-80.00 mg, crospovidone 14.00-25.00 mg, povidone 15.00 mg, colloidal silicon dioxide 8.00 mg, stearic acid 3.00 mg. It is also proposed to use the dosage form described above for the treatment and/or prevention of viral diseases.
EFFECT: invention ensures improved technological characteristics and increased stability of the product relative to the known analogue, in particular, the composition retains its properties during transportation and long-term storage, including long-term storage within the 4 main climatic zones without deterioration of the main quality indicators.
8 cl, 5 tbl, 4 ex
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Authors
Dates
2021-07-08—Published
2020-06-15—Filed