FIELD: medicine; chemistry; pharmaceutics.
SUBSTANCE: group of inventions relates to the field of chemical-pharmaceutical industry and medicine and relates to a pharmaceutical composition and a drug exhibiting preventive and/or therapeutic antiviral activity, and use thereof. Pharmaceutical composition contains, in therapeutically effective amounts, favipiravir in the form of a free base and at least one pharmaceutically acceptable salt of a proteinogenic amino acid in weight ratio of favipiravir to an amino acid equal to 1.0:0.1–1.0:1.1, respectively. Medicinal agent contains said pharmaceutical composition and at least one pharmaceutically acceptable excipient. Also presented is using the above pharmaceutical composition for preparing a drug exhibiting preventive and/or therapeutic antiviral activity.
EFFECT: group of inventions widens the range of antiviral agents, the pharmaceutical composition and drug described above have high antiviral activity and have improved stability as compared to formulations containing favipiravir salts.
57 cl, 2 tbl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
ANTIVIRAL PHARMACEUTICAL COMPOSITION CONTAINING FAVIPIRAVIR AND AN AMINO ACID, MEDICINAL PRODUCT CONTAINING SAID COMPOSITION, AND APPLICATION THEREOF FOR TREATING AND/OR PREVENTING VIRAL INFECTIONS | 2021 |
|
RU2783282C1 |
ANTIVIRAL PHARMACEUTICAL COMPOSITION CONTAINING FAVIPIRAVIR AND AMINO ACID, DRUG CONTAINING IT, AS WELL AS THEIR USE FOR TREATING AND/OR PREVENTING VIRAL INFECTIONS | 2022 |
|
RU2814927C1 |
ANTIVIRAL PHARMACEUTICAL COMPOSITION CONTAINING FAVIPIRAVIR AND AMINO ACID HYDRATE AND/OR ITS PHARMACEUTICALLY ACCEPTABLE SALT | 2021 |
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PHARMACEUTICAL COMPOSITION AND MEDICINAL AGENT CONTAINING NOVEL DERIVATIVES OF FAVIPIRAVIR | 2023 |
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METHOD OF PRODUCING NOVEL DERIVATIVES OF FAVIPIRAVIR | 2023 |
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ANTIVIRAL COMPOSITION | 2020 |
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ANTIVIRAL COMPOSITION | 2020 |
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Authors
Dates
2025-05-05—Published
2022-11-02—Filed