FIELD: chemical-pharmaceutical industry; medicine.
SUBSTANCE: group of inventions relates to a pharmaceutical composition and a medicinal agent exhibiting preventive and/or therapeutic antiviral activity, and use thereof. Pharmaceutical composition contains in therapeutically effective amounts favipiravir and at least one aliphatic mono- or diaminomonocarboxylic non-proteinogenic amino acid with weight ratio of favipiravir to amino acid 1.0:0.1–1.0:1.20 respectively. Medicinal agent contains the above pharmaceutical composition and at least one pharmaceutically acceptable excipient. Also disclosed is use of said pharmaceutical composition for preparing a drug exhibiting preventive and/or therapeutic antiviral activity.
EFFECT: group of inventions provides a wider range of antiviral agents, pharmaceutical composition and medicinal agent described above have improved processing characteristics, stability and bioavailability.
52 cl, 2 tbl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
ANTIVIRAL PHARMACEUTICAL COMPOSITION CONTAINING FAVIPIRAVIR AND AN AMINO ACID, MEDICINAL PRODUCT CONTAINING SAID COMPOSITION, AND APPLICATION THEREOF FOR TREATING AND/OR PREVENTING VIRAL INFECTIONS | 2021 |
|
RU2783282C1 |
ANTIVIRAL PHARMACEUTICAL COMPOSITION CONTAINING FAVIPIRAVIR AND AMINO ACID HYDRATE AND/OR ITS PHARMACEUTICALLY ACCEPTABLE SALT | 2021 |
|
RU2789612C1 |
ANTIVIRAL COMPOSITION | 2020 |
|
RU2740660C1 |
ANTIVIRAL COMPOSITION | 2020 |
|
RU2740657C1 |
ANTI-RNA VIRAL, INCLUDING ANTI-CORONAVIRUS AGENT - SUBSTITUTED QUINOXALINE, PHARMACEUTICAL COMPOSITION AND APPLICATIONS | 2020 |
|
RU2744429C1 |
ANTIVIRAL COMPOSITION | 2020 |
|
RU2751108C1 |
ANTI-COVID-19 (SARS-COV-2) VIRAL PHARMACEUTICAL COMPOSITION | 2020 |
|
RU2731932C1 |
ANTI-SARS-CoV-2-VIRAL PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 2020 |
|
RU2764444C1 |
COMBINATION OF MIRTAZAPINE AND TIZANIDINE FOR USE IN PAIN DISORDERS | 2019 |
|
RU2736713C1 |
STABLE LYOPHILIZATES CONTAINING 5,10-METHYLENE-(6R)-TETRAHYDROFOLIC ACID | 2018 |
|
RU2796570C2 |
Authors
Dates
2024-03-06—Published
2022-11-02—Filed