DYNAMIC ANTIRETROVIRAL HIV-INFECTION THERAPY Russian patent published in 2021 - IPC A61K31/5365 A61K31/506 A61K31/52 A61P31/18 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to a method of treating HIV infection. The method consists in the fact that when HIV infection is detected in a patient treatment is started by administering three antiretroviral drugs, namely a non-nucleoside reverse transcriptase inhibitor or a protease inhibitor, or an integrase inhibitor such as dolutegravir, in combination with two nucleoside reverse transcriptase inhibitors, one of which is tenofovir, for at least 6 months, and then after the level of HIV RNA in the blood reaches less than 50 copies/ml and the level of CD4 T-lymphocytes is at least 450 cells/mcl in at least two measurements at an interval of 1 month, lifelong administering of dolutegravir at a dosage of 50 mg and emtricitabine at a dosage of 200 mg is started.

EFFECT: proposed method can be used for effective treatment of patients with HIV infection in order to minimize risks of developing adverse events in conducted therapy.

4 cl, 1 dwg, 3 ex