METHOD OF TREATING PATIENTS WITH HIV INFECTION Russian patent published in 2025 - IPC A61K31/7072 A61K31/727 A61P31/18 

FIELD: medical science.

SUBSTANCE: invention relates to medicine, specifically to virology, and can be used for treating patients with HIV infection. A patient with viral load less than 50 copies of HIV RNA is administered zidovudine by direct endolymphatic infusion into a drained peripheral lymphatic vessel of an internal surface of an upper one-third of shin or middle one-third of thigh in dose of 1-2 mg per kg of patient’s body weight, but no more than 200 mg of zidovudine in one infusion. Treatment is carried out according to the schedule: two infusions daily for 21-25 days, wherein before and after the first infusion of zidovudine, endolymphatic heparin is administered at dose of 5000 IU and 2500 IU, respectively, and after 10-12 hours, a second infusion of zidovudine is carried out, after which endolymphatic heparin is administered in dose of 2500 IU.

EFFECT: method provides CD4-lymphocyte count recovery to normal and maintenance of an undetectable viral load for at least 2 months after the course of the endolymphatic therapy with using zidovudine.

2 cl, 1 ex