FIELD: pharmaceutics.
SUBSTANCE: invention relates to the compounds of the general formulas listed below, their stereoisomers and pharmacologically acceptable salts, a pharmaceutical composition based on them, their application and method for therapeutic treatment of hypertension, or prehypertension, and/or myocardial fibrosis, and their use in the preventive and/or therapeutic treatment of hypertension and/or fibrosis, including the injection of an effective amount of the compound according to clause 1.
or 
.
In general formulas, X is selected from 
and 
Y is A or CH2-A, A is selected from 
and 
and Z is selected from 
and 
.
EFFECT: compositions for the treatment of hypertension and/or fibrosis are obtained.
11 cl, 12 dwg, 2 ex
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