COMPOSITIONS FOR TREATING FIBROSIS AND FIBROSIS-RELATED CONDITIONS Russian patent published in 2020 - IPC C07C39/15 C07C47/575 C07C65/03 C07C211/29 C07C217/48 C07D207/267 C07D207/36 C07D207/408 C07D207/448 C07D209/48 C07D233/78 C07D261/14 C07D263/42 C07D263/44 A61K31/165 A61K31/192 A61K31/381 A61K31/42 A61P1/12 A61P9/10 A61P13/12 

FIELD: chemistry.

SUBSTANCE: present invention relates to a novel compound of formula:

or to its pharmacologically acceptable salt. In said structural formulas A is selected from: partially saturated or unsaturated 5- or 6-member heterocyclyl selected from pyrrolyl, pyrazolyl, imidazolyl, triazolyl, imidazolidinyl, pyrrolidinyl, pyrrolidinylidene, dihydropyrrolyl, isoxazolyl-dihydrooxazolyl, isoxazolidinyl, oxazolidinyl and oxazolyl, where said partially saturated or unsaturated 5- or 6-member heterocyclyl is optionally substituted with one or more oxo, C_1-6alkyl, amino, hydroxyl or halogen; C_1-6alkoxylamine; C_1-6alkylamine, optionally substituted with one or more substitutes, which are C_1-6alkyl, C_1-6haloalkyl, hydroxyl or halogen; C_0-6alkyl-carboxylic acid; C_1-6alkylhydroxyl; saturated or unsaturated C_0-6alkyl-bicyclic-heterocyclyl, selected from indolyl, isoindolyl, indolinyl and isoindolinyl, where said saturated or unsaturated C_0-6alkyl-bicyclic-heterocyclyl is optionally substituted with one or more oxo; and saturated or unsaturated C_1-6alkoxy-bicyclic-heterocyclyl, selected from indolyl, isoindolyl, indolinyl and isoindolinyl, where said C_1-6alkoxy-bicyclic-heterocyclyl is optionally substituted with one or more oxo.

EFFECT: compound is used for preventive or therapeutic treatment of fibrosis.

27 cl, 22 dwg, 15 ex