FIELD: chemistry.
SUBSTANCE: invention relates to a complex compound of germanium containing an acyclic polyol, as well as an amino acid or hydroxy acid and optionally, additionally, a metal cation, by the general formula (I): Ge[L]a[A]b[M]c (I), wherein L is an acyclic polyol by the general formula (HOCH2[CH(OH)]nCH2OH), wherein n = 2, 3, or 4, A is an amino acid or hydroxy acid, M is a cation of a metal from the group 2 or 12 of the periodic system, a = 1 or 2, b = 1, wherein c = 0 when A constitutes an amino acid or c = 0 or 1 when A constitutes a hydroxy acid, wherein when A constitutes a hydroxy acid and is not equal to 0, said complex compound optionally constitutes ethanol solvate. All Ls in the complex compound are the same or different. Also proposed is a method for synthesising complex compounds of germanium.
EFFECT: proposed compounds exhibit antibacterial activity and can be used to prevent or treat various oral diseases.
8 cl, 6 dwg, 6 ex
Title | Year | Author | Number |
---|---|---|---|
GERMANIUM COMPOUNDS WITH POLYOLS AND POLYBASIC CARBOXYLIC ACIDS, METHOD OF THEIR PREPARATION AND USE | 2023 |
|
RU2812547C1 |
COMPLEX GERMANIUM CONNECTIONS WITH AMINO ACIDS AND LIPOIC ACID | 2015 |
|
RU2626954C2 |
COMPLEXES OF GERMANIUM WITH PURINE NITROGENOUS BASES, METHODS FOR PRODUCTION THEREOF AND MEDICINAL AGENTS CONTAINING SAID COMPLEXES | 2012 |
|
RU2487878C1 |
COMPLEX COMPOUNDS OF GERMANIUM WITH PEPTIDES AND PEPTIDES AND HYDROXYCARBONIC ACIDS | 2016 |
|
RU2636788C2 |
COMPLEX COMPOUNDS OF GERMANIUM WITH AMINO ACIDS AND CARBOCYLIC ACIDS | 2012 |
|
RU2476436C1 |
METHODS FOR ELECTROLYTIC PRODUCTION OF ERYTHROSE OR ERYTHRITOL | 2006 |
|
RU2433211C2 |
TRIETHANOLAMINE TRICYCLIC ORGANOGERMANIC DERIVATIVES CITRATE SALTS AND METHOD FOR THEIR PREPARING | 2005 |
|
RU2293086C1 |
NEW INHIBITORS OF BACTERIAL GLUTAMINYL CYCLASES FOR USE IN THE TREATMENT OF PERIODONTAL AND RELATED DISEASES | 2019 |
|
RU2805298C2 |
PROCESS FOR MANUFACTURE OF SEMICONDUCTOR DEVICES COMPRISING CHEMICAL MECHANICAL POLISHING OF ELEMENTAL GERMANIUM AND/OR SiGe MATERIAL IN PRESENCE OF CMP (CHEMICAL MECHANICAL POLISHING) COMPOSITION COMPRISING A SPECIFIC ORGANIC COMPOUND | 2012 |
|
RU2605941C2 |
SALTS OF 1-HYDROXYGERMATRANE WITH OXY-, KETO- AND DICARBONIC ACIDS | 2006 |
|
RU2333912C1 |
Authors
Dates
2021-08-11—Published
2020-10-16—Filed