METHOD FOR DIFFERENTIAL DIAGNOSIS OF PANCREATIC HEAD ADENOCARCINOMA AND CHRONIC PSEUDOTUMOR PANCREATITIS IN PATIENTS WITH MECHANICAL JAUNDICE Russian patent published in 2021 - IPC A61B6/03 A61B5/275 

FIELD: medicine.

SUBSTANCE: invention relates to the field of medicine, in particular to radiology, and can be used for the differential diagnosis of pancreatic head adenocarcinoma and chronic pseudotumor pancreatitis in patients with mechanical jaundice. The pathological process is detected by spiral computed tomography (SCT). At the same time, before performing a standard multiphase scan, a perfusion scan is performed and a label is inserted into the image of the abdominal aorta using a computer program. The “density-time” dependence graph is plotted. A qualitative analysis of the obtained images of the head of the pancreas is carried out using color parametric maps of the blood flow rate and the rate of increase in the density of the contrast agent in the tissue. The blood flow rate and the rate of increase in the density of the contrast agent in the tissue in the area of interest are determined. In the presence of blue staining of the zone of the pathological process of the pancreatic head on color parametric maps of the blood flow rate and the rate of increase in the density of the contrast agent in the tissue, in the absence of a rise in the curve on the density-time graph, as well as at the values of the blood flow velocity of 47.10±12.47 ml/100 g/min and the rate of increase in the density of the contrast agent in the tissue of 1.54±3.45 HU/min adenocarcinoma of the head of the pancreas is diagnosed. In the presence of red-yellow staining of the zone of the pathological process of the pancreatic head, the presence of a rise in the curve on the “density-time” graph and the values of the blood flow rate of 81.7±17.2 ml/100 g/min and the rate of increase in the density of the contrast agent in the tissue of 3.2±1.35 HU/min chronic pseudotumor pancreatitis is diagnosed in patients with mechanical jaundice.

EFFECT: method provides differential diagnosis of pancreatic head adenocarcinoma and chronic pseudotumor pancreatitis in patients with mechanical jaundice due to the declared quantitative and qualitative diagnostic criteria.

1 cl, 14 dwg, 2 ex