FIELD: medicine.
SUBSTANCE: invention relates to a compound by the formula (2a), which can be applied as a pro-drug for inhibiting deacetylase UDP(uridine-5'-diphosphate)-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine (LpxC). In the formula (2a), X constitutes CH; Z constitutes 
and M+ constitutes a pharmaceutically acceptable monovalent cation selected from the group consisting of Li+, K+, Na+, NH4+, NH3+С(СН2ОН)3 or NH2+(CH2CH3)2. The invention also relates to a pharmaceutical composition for use as a pro-drug for inhibiting deacetylase UDP(uridine-5'-diphosphate)-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine (LpxC), containing an effective amount of said compound in a mixture with at least one pharmaceutically acceptable excipient, diluent or carrier, and to a method for treating an infection caused by gram-negative bacteria in a non-human animal in need thereof, including administering a therapeutically effective amount of said compound to a non-human animal in need thereof.
EFFECT: compound according to the disclosed invention can be used as a pro-drug for inhibiting deacetylase.
10 cl, 2 tbl, 32 ex
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