PYRIDAZINE DERIVATIVES AS RORc MODULATORS Russian patent published in 2021 - IPC C07D401/14 C07D403/14 C07D405/14 C07D413/14 C07D409/14 A61K31/502 A61P17/06 A61P37/00 

Abstract RU 2757571 C2

FIELD: medicine.

SUBSTANCE: present invention relates to compounds that modulate a function of an orphan receptor RORc (RORy) related to retinoid receptors, namely to specific compounds as they are presented in the claims. A pharmaceutical composition and the use of compounds for the preparation of a drug and the treatment or prevention of a disease mediated by the RORc receptor are also proposed.

EFFECT: obtaining new organic compounds that modulate the function of the orphan receptor RORc related to retinoid receptors and that can be used for the treatment of autoimmune diseases.

10 cl, 2 tbl, 88 ex

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RU 2 757 571 C2

Authors

Bronner, Sara M.

Krouford, Dzhejms Dzh.

Kridlend, Endryu

Ser, Patrik

Fauber, Bendzhamin

Gansiya, Emanuela

Gobbi, Alberto

Kherli, Kristofer

Killen, Dzhonatan

Li, Vendi

Rene, Olive

Van Nil, Monik Bodil

Uord, Styuart

Uinship, Pol

Zbig, Dzhejson

Dates

2021-10-18Published

2017-10-31Filed