Patenton — panteon of patents

(19)

RU

(11)

2 768 019

(13)

C2

(51)

IPC

C07K14/705(2006-01-01)

C07K19/00(2006-01-01)

C12N5/783(2010-01-01)

C12N5/10(2006-01-01)

C12N15/09(2006-01-01)

A61K35/17(2015-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2017121892, 2015-12-23

(24)

Start date

2015-12-23

(22)

Actual filing date

2015-12-23

(45)

Published

2022-03-23

(72)

Inventor

Pyule MartenKordoba ShonOnuokha SimobiTomas Sajmon

(73)

Holder

Otolus Limited

CELL Russian patent published in 2022 - IPC C07K14/705 C07K19/00 C12N5/783 C12N5/10 C12N15/09 A61K35/17 A61P35/00 

Abstract RU 2768019 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, specifically to the production of a cytolytic immune effector cell for the adoptive cell transfer; it can be used in medicine. The produced cell co-expresses the first chimeric antigen receptor (hereinafter – CAR) binding to CD19 and the second CAR binding to CD22 on the cell surface; it can be used for the effective therapy of malignant tumor that is characterized in the presence of cells that express CD19 and/or CD22.

EFFECT: obtaining a cell for the therapy of malignant tumors.

19 cl, 14 dwg, 7 tbl, 4 ex

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RU 2 768 019 C2

Authors

Pyule Marten

Kordoba Shon

Onuokha Simobi

Tomas Sajmon

Dates

2022-03-23—Published

2015-12-23—Filed

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