FIELD: medicine.
SUBSTANCE: invention relates to compounds or pharmaceutically acceptable salts thereof, constituting prodrugs of ketamine, selected from the following structures:
The invention also relates to a pharmaceutical composition modulating the reaction of the NMDA receptor based on the described compounds.
EFFECT: new compounds and a pharmaceutical composition based thereon are produced, applicable in medicine for treating diseases associated with the NMDA receptor, including depression and pain.
15 cl, 6 tbl, 109 ex
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Authors
Dates
2021-10-01—Published
2019-01-08—Filed