FIELD: medicine.
SUBSTANCE: group of inventions relates to agents and materials for stimulating hemostasis and sealing tissue. A method for forming a powdered hemostatic composition is disclosed, including stages, at which suspension of a mixture containing particles of fibrinogen, thrombin, and fibers of oxidized regenerated cellulose (hereinafter – ORC) is formed in a non-aqueous solvent with a low boiling temperature, providing evaporation of the solvent under environmental conditions; suspension is sprayed through a nozzle onto substrate; the non-aqueous solvent is waited to evaporate; the composition is separated from substrate, the composition is sieved and thus a powdered hemostatic composition is formed. A powdered hemostatic composition containing at least partially integrated agglomerated ORC fibers, fibrinogen and thrombin, and a method for the treatment of a wound by using this powdered hemostatic composition are also disclosed.
EFFECT: group of inventions provides hemostatic material that has high uniformity, integrity, high adhesion strength and quickly forms gel/clot.
18 cl, 9 dwg, 4 tbl, 8 ex
| Title | Year | Author | Number |
|---|---|---|---|
| HAEMOSTATIC COMPOSITION | 2016 |
|
RU2741304C2 |
| HEMOSTATIC POWDERS OF OXIDED REGENERATED CELLULOSE AND METHODS OF THEIR PRODUCTION | 2013 |
|
RU2629199C2 |
| HAEMOSTATIC POWDERS OF OXIDISED REGENERATED CELLULOSE AND METHODS FOR PRODUCTION THEREOF | 2013 |
|
RU2696575C2 |
| HEMOSTATIC BIOLOGICALLY ABSORBABLE DEVICE WITH POLYETHYLENE GLYCOL AS A BINDING SUBSTANCE | 2012 |
|
RU2646728C1 |
| HEMOSTATIC BIOLOGICALLY ABSORBED DEVICE WITH POLYETHYLENE GLYCOL AS BINDING SUBSTANCE | 2012 |
|
RU2627426C2 |
| HAEMOSTATIC MIXTURE OF SHORT AND LONG CELLULOSE-BASED FIBERS | 2016 |
|
RU2731371C2 |
| COMPACT HEMOSTATIC CELLULOSE UNITS | 2016 |
|
RU2767670C2 |
| COMPACTED HAEMOSTATIC CELLULOSE AGGREGATES | 2016 |
|
RU2702339C1 |
| HEMOSTATIC MATERIALS AND DEVICES WITH GALVANIC PARTICULATE MATERIAL | 2012 |
|
RU2628877C2 |
| FIBRINOGEN CONTENT ANALYSIS | 2012 |
|
RU2619256C2 |
