METHOD FOR DETERMINING THE ADSORPTION CAPACITY OF GRANULAR OSTEOCONDUCTIVE BONE GRAFT MATERIAL Russian patent published in 2021 - IPC G01N30/00 A61C7/00 A61L27/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to maxillofacial surgery, and discloses a method for determining the adsorption capacity of granular osteoconductive osteoplastic material (GOOM). The method is characterized by the fact that dust and air bubbles are removed from the GOOM by the degassing method, which includes the stages of passive and active degassing using physical and chemical methods, namely heating in a thermostat in physiological solution and sonication using a citric acid solution. Next, the difference between the initial liquid volume and the liquid volume after passive degassing is calculated, as well as the difference between the liquid volumes before and after active degassing, then the indicated values are summed up, the resulting sum calculated for 1 ml of GOOM is the adsorption capacity of granular osteoconductive material. The method is aimed at optimizing the reparative regeneration of bone tissue by the method for directed bone regeneration. The use of the method for directed bone regeneration to eliminate a bone defect implies the use of bone-grafting materials as a matrix for reconstruction with external-internal surfaces and spaces available for the adsorption of bone growth factors.

EFFECT: method allows, due to the proposed degassing method, increasing the adsorption capacity of the original GOOM, optimizing the biotransformation of the osteoplastic material placed in the recipient bed into native bone, which will optimize the treatment time, avoid postoperative complications and repeated surgical interventions.

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