FIELD: pharmaceutics.
SUBSTANCE: invention relates to the use of compounds of the general formula (1), in which R1 means a group of formula (2) or (3); A represents CH2, R2 and R3 independently represent hydrogen, R4 and R6 independently represent hydrogen or tert-butyl; R5 means naphthyl-(C1-C6)-alkyl or phenyl-ethyl, R7 and R8 independently represent ethyl or benzyl, or its stereoisomer or pharmacologically acceptable salt to reduce apoptosis of retinal ganglion cells of the eye.
EFFECT: compounds according to the invention can be used in medicine for the preparation of pharmaceutical compositions for the prevention and treatment of eye diseases.
9 cl, 1 tbl
| Title |
Year |
Author |
Number |
| INHIBITORS OF NEUTRAL ENDOPEPTIDASE (NEP) AND HUMAN SOLUBLE ENDOPEPTIDASE (HSEP) FOR REDUCTION IN HARMFUL EFFECTS OF PERFUSION ORGAN DEFICIENCY |
2019 |
|
RU2782919C2 |
| TREATMENT OF EYE DISEASES SUCH AS MACULAR DEGENERATION, GLAUCOMA AND DIABETIC RETINOPATHY WITH MEDICATIONS THAT ELIMINATE AGING CELLS |
2018 |
- Hopkins, Jill
- Tsuruda, Pam
- Chapman, Claude
- Sweigard, Harry
- Poon, Yan
- Marquess, Daniel
- David, Nathaniel
- Dananberg, Jamie
- Laberge, Remi-Martin
|
RU2815482C2 |
| USE OF FORMYL PEPTIDE RECEPTOR 2 AGONISTS FOR TREATING INFLAMMATORY EYE DISEASES |
2014 |
- Viswanath, Veena
- Beard Richard L.
- Donello John E
|
RU2768730C2 |
| USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING INFLAMMATORY EYE DISEASES |
2014 |
- Visvanat Vina
- Bird Richard L.
- Donello Dzhon E.
|
RU2663911C2 |
| DIPEPTIDYLPEPTIDASE-4 INHIBITORS FOR LOCAL OPHTHALMOLOGICAL TREATMENT OF NEURODEGENERATIVE RETINAL DISEASES |
2017 |
- Simo Canonge, Rafael
- Hernandez Pascual, Cristina
|
RU2744878C2 |
| METHOD FOR TREATING ATROPHIC AGE RELATED MACULAR DEGENERATION |
2009 |
- Robinson Majkl R.
- Blanda Uendi M.
- Khyus Patrik M.
- Berke Dzhejms A.
- Vitkap Skott M.
|
RU2668371C2 |
| METHOD OF TREATING ATROPHIC AGE-RELATED MACULAR DEGENERATION |
2009 |
- Robinson Majkl R.
- Blanda Uehndi M.
- Kh'Jus Patrik M.
- Berke Dzhehjms A.
- Vitkap Skott M.
|
RU2521338C9 |
| DERIVATIVES OF N-UREA-SUBSTITUTED AMINOACIDS AS MODULATORS OF FORMYL-PEPTIDE RECEPTOR |
2014 |
- Bird Richard L.
- Duong Ten T.
- Donello Dzhon E.
- Visvanat Vina
- Garst Majkl E.
|
RU2696581C2 |
| METHOD OF TREATING ELEVATED INTRAOCULAR PRESSURE USING INTRAOCULAR SUSTAINED RELEASE DRUG DELIVERY SYSTEM |
2014 |
- Robinson Majkl R.
- Berke Dzhejms A.
- Lyu Khuj
- Orilla Verner S.
- Spejda Lon T.
- Uitkap Skott
- Gebremeskel Alazar N.
- Khyus Patrik M.
- Syuj Kun
- Do Marianna M.
|
RU2664686C2 |
| ANTI-INFLAMMATORY AND MYDRIATIC INTRA-CHAMBER SOLUTIONS FOR INHIBITION OF POSTOPERATIVE INFLAMMATORY EYE CONDITIONS |
2015 |
- Demopulos, Gregory, A.
- Florio, Vincent, A.
|
RU2750296C2 |
