NON-GENETIC MODIFICATION OF ENVELOPED VIRUSES Russian patent published in 2021 - IPC C12N7/00 

Abstract RU 2760521 C2

FIELD: biotechnology.

SUBSTANCE: described is a modified enveloped virus selected from the group consisting of: herpes simplex virus 1 (HSV-1), herpes simplex virus 2 (HSV-2), vaccinia virus, vesicular stomatitis virus (Indiana fever) (VSV), measles virus (MeV), Maraba virus and Newcastle disease virus (NDV), wherein said virus has at least one anti-tumour, tumour-specific peptide, non-genetically attached to the viral envelope or injected into/through the viral envelope. Also proposed is a pharmaceutical composition for treating cancer, containing: a modified enveloped virus according to any of the claims 1 to 17 and a corresponding carrier. Also described are methods for treating cancer.

EFFECT: invention expands the range of means of treating cancer.

24 cl, 13 dwg, 1 ex

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RU 2 760 521 C2

Authors

Cherullo Vinchentso

Kapasso Kristian

Ilosmaki Erkko

Dates

2021-11-26Published

2017-09-06Filed