METHOD FOR MINERALIZATION OF ORGANIC POLYCAPROLACTONE FIBERS WITH CALCIUM CARBONATE MICROPARTICLES Russian patent published in 2021 - IPC D01F11/04 D01F11/12 A61F2/00 

FIELD: composite materials.

SUBSTANCE: invention relates to a method for the production of a composite material consisting of organic polycaprolactone fibers, calcium carbonate microparticles and magnetite nanoparticles. The resulting material can be used in regenerative medicine, mainly as a tissue engineering framework. The method for mineralization of organic polycaprolactone fibers with calcium carbonate microparticles, the vaterite modification includes adding a solution of Fe₃O₄ magnetite to polycaprolactone fibers, ultrasonic treatment of this mixture, adding solutions of calcium chloride salts CaCl₂ and sodium carbonate Na₂CO₃ to the mixture, washing the resulting material with ethyl alcohol and drying it, while solutions of CaCl₂ and Na₂CO₃ salts with a concentration of 0.25 - 1.0 M are added to the mixture in a volume ratio of 1:1:1 (CaCl₂: Na₂CO₃: Fe₃O₄), without interrupting the ultrasonic treatment process, while drying is carried out in a drying cabinet at 43-47°C for 10-15 minutes, and the size of magnetite nanoparticles is selected in the range from 10 to 80 nm.

EFFECT: technical result is the improved the quality of the resulting material while ensuring sufficient magnetic susceptibility.

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