METHOD FOR OBTAINING A CAROTENOID COMPLEX FROM STARFISH Russian patent published in 2021 - IPC A61K35/56 B01D11/02 B01D15/08 B01D21/26 

FIELD: chemistry.

SUBSTANCE: invention relates to the field of chemistry, namely, to a method for obtaining a carotenoid complex from starfish of the species Patiria pectinifera. The method includes extraction of raw materials from Patiria pectinifera starfish with an aqueous solution of organic or inorganic food acid at pH 1-2 with a ratio of raw materials: acid 1:1-1.2 for a certain time, then repeated extraction of raw materials with the food acid, combining the extracts obtained, centrifugation under certain conditions and filtration, adding to the resulting filtrate containing a water-soluble protein-carotenoid complex, a solution of organic or inorganic food acid until pH 1-2 is reached and passing the filtrate through a column with polychrome-1, balanced aqueous solution of the same food acid, pH 1-2, washing the column sequentially with water and a gradient of ethyl alcohol, elution of the target product with ethyl alcohol, evaporation of the eluate in vacuum, dissolution of the resulting concentrate in ethyl alcohol, settling, centrifugation and evaporation of the alcohol solution in vacuum.

EFFECT: invention provides an increase in the content of astaxanthin in the carotenoid complex by an average of 1.3 times.

1 cl, 4 dwg, 2 ex