ANTIBODIES AGAINST THE PROGRAMMED DEATH LIGAND (PD-L1) AND APPLICATION THEREOF Russian patent published in 2021 - IPC C07K16/28 C12N5/10 C12N15/13 C12N15/85 A61K39/395 A61P35/00 

Abstract RU 2761638 C1

FIELD: biotechnology.

SUBSTANCE: described are an antibody against the programmed death ligand (PD-L1) and an application thereof for producing a medicinal product for treating a neoplastic disease, an isolated nucleic acid molecule, a pharmaceutical composition, an expression vector, a host cell for expression of the antibody or an antigen-binding fragment thereof, and a method for obtaining the antibody.

EFFECT: invention provides a possibility of obtaining a new antibody against the programmed death ligand and effectively using said antibody in treatment or prevention of conditions associated with PD-L1, in particular, such as a PD-L1-positive tumour.

21 cl, 8 dwg, 2 tbl, 10 ex

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RU 2 761 638 C1

Authors

Wang, Haibin

Hu, Feng

Zhang, Xuan

Jiao, Jingyu

Wu, Zhenhua

Gao, Dong

Dates

2021-12-13Published

2019-06-06Filed