IMMUNOGENIC COMPOSITIONS FOR USE IN PNEUMOCOCCAL VACCINES Russian patent published in 2021 - IPC A61K39/09 A61P31/04

Abstract RU 2762723 C2

FIELD: medicine.

SUBSTANCE: use of an immunogenic composition for immunizing a patient against S. pneumoniae infection of serotypes 18A, 18B and 18F is proposed. The specified composition contains at least one glycoconjugate from capsular saccharide of S. pneumoniae of serotype 18C, where the specified glycoconjugate is obtained by reductive amination. The composition additionally contains glycoconjugates from capsular saccharide of S. pneumoniae of serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 19A, 19F and 23F, but does not contain capsular saccharide of S. pneumoniae of serotypes 18A, 18B and 18F. A set for protection against S. pneumoniae of serogroup 18, containing the specified composition, and a method for testing the capability of an immunogenic composition of protecting against S. pneumoniae of serogroup 18 are also proposed.

EFFECT: inventions provide protection against S. pneumoniae of serogroup 18.

17 cl, 6 dwg, 1 tbl, 1 ex

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RU 2 762 723 C2

Authors

Cooper, David

Jansen, Kathrin Ute

Pride, Michael William

Dates

2021-12-22—Published

2018-01-05—Filed