METHOD FOR CHOOSING A THERAPEUTIC DOSE OF CHOLECALCIFEROL FOR A PATIENT WITH INSUFFICIENT PROVISION OR VITAMIN D DEFICIENCY WHO HAS UNDERGONE BREAST CANCER Russian patent published in 2021 - IPC G01N33/52 G01N33/82 A61B5/1468 A61P3/02 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely oncology, and reveals a method for choosing a therapeutic dose of cholecalciferol for a patient with vitamin D insufficiency or deficiency who has undergone breast cancer. The method is characterized by calculating the difference between the quantitative indicators of Imax, MDA, DEC obtained 6 months after the start of therapy involving the intake of cholecalciferol at the selected therapeutic dose and the initial value of the above quantitative indicators, in the case of a decrease in Imax, a decrease in the levels of MDA, DEC in the venous blood of the patient within the reference values, it is concluded that the selected therapeutic dose of cholecalciferol for the specified patient is optimal.

EFFECT: proposed dose of 5000 ME of cholecalciferol intake in patients with vitamin D insufficiency or deficiency who have undergone breast cancer provides the reduction of lipid peroxidation indicators, such as Imax and MDA, a decrease in the level of endothelial cells DEC, indicating isostasy of the homeostasis of oxidation processes and normalization of the vascular endothelial function.

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