FIELD: organic chemistry and pharmacology.
SUBSTANCE: invention relates to the field of organic chemistry and pharmacology, namely to (Z)-9-aroyl-8-hydroxy-6-(2-hydroxyphenyl)-2-(((Z)-2-oxoindolin-3-ylidene)hydrazono)-1-thia-3,6diazaspiro [4.4]non-8-en-4,7-dione of the general formula below, where R=H (a), Br (b), Cl (c), NO2 (d).
EFFECT: new compounds with antimicrobial activity have been obtained, which can be used in pharmacology as potential drugs with antimicrobial properties.
1 cl, 1 tbl, 5 ex
| Title |
Year |
Author |
Number |
| ANTIOXIDANT BASED ON 2-[(R-BENZYLIDENE)HYDRAZONO]-8-HYDROXY-6-(2-HYDROXYPHENYL)-9-(4-BROMBENZOYL)-1-THIA-3,6-DIAZASPIRO[4.4]NONA-8-EN-4,7-DIONES |
2023 |
- Lukmanova Dzhamilia Nailevna
- Mashevskaia Irina Vladimirovna
- Dmitriev Maksim Viktorovich
|
RU2806329C1 |
| APPLICATION OF 2-[(R-BENZYLIDENE)HYDRAZONO]-8-HYDROXY-6-(2-HYDROXYPHENYL)-9-AROYL-1-THIA-3,6-DIAZASPIRO[4.4]NONA-8-EN-4,7-DIONES AS AGENTS WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Mashevskaia Irina Vladimirovna
- Lukmanova Dzhamilia Nailevna
- Apushkin Danila Iurevich
- Utushkina Taisiia Andreevna
- Iakushina Karolina Evgenevna
- Andreev Aleksandr Igorevich
|
RU2783241C1 |
| ANTITUBERCULOSIS AGENT BASED ON (Z)-9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-2-(((E)-PYRIDIN-3-YLMETHYLENE)HYDRAZONO)-1-THIA-3,6-DIAZOSPIRO[4.4]NON-8-ENE-4,7-DIONES |
2023 |
- Lukmanova Dzhamilia Nailevna
- Mashevskaia Irina Vladimirovna
- Balandina Svetlana Iurevna
|
RU2808987C1 |
| METHOD OF PRODUCING 2-AMINO-9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-1-THIA-3,6-DIAZASPIRO[4.4]NONA-2,8-DIENE-4,7-DIONE |
2019 |
- Maslivets Andrej Nikolaevich
- Kobelev Aleksandr Ivanovich
- Stepanova Ekaterina Evgenevna
- Balandina Svetlana Yurevna
|
RU2707195C1 |
| APPLICATION OF 8-HYDROXY-6-(2-HYDROXYETHYL)-9-(4-METHYLBENZOYL)-2-PHENYL-1-THIA-3,6-DIAZASPIRO[4.4]NON-2,8-DIENE-4,7-DIONE AS AN AGENT WITH ANTIMICROBIAL ACTIVITY AGAINST THE S. AUREUS CULTURE |
2023 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2803888C1 |
| METHOD FOR PREPARATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-2-PHENYL-1-THIA-3,6-DIAZASPIRO[4,4]NON-2,8-DIENE-4,7-DIONES |
2016 |
- Stepanova Ekaterina Evgenevna
- Maslivets Andrej Nikolaevich
- Kobelev Aleksandr Ivanovich
- Balandina Svetlana Yurevna
|
RU2631432C1 |
| APPLICATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-IMINO-1-THIA-3,6-DIAZASPIRO[4,4]NON-8-EN-4,7-DIONES AS AGENTS, WITH ANTIMICROBIAL ACTIVITY |
2022 |
- Maslivets Andrei Nikolaevich
- Tretiakov Nikita Alekseevich
- Balandina Svetlana Iurevna
|
RU2790479C1 |
| USE OF 9-BENZOYL-8-HYDROXY-6-(2-HYDROXYETHYL)-2-PHENYL-1-THIA-3,6-DIAZASPIRO[4.4]NONE-2,8-DIEN-4,7-DIONE AS AN ANTIFUNGAL DRUG |
2022 |
- Maslivets Andrei Nikolaevich
- Tretiakov Nikita Alekseevich
- Balandina Svetlana Iurevna
|
RU2791043C1 |
| APPLICATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-1,3-DIALKYL-2-THIOXO-1,3,6-TRIAZASPIRO[4.4 NON-8-ENE-4,7-DIONES AS AGENTS WITH ANTIMICROBIAL ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Tretyakov Nikita Alekseevich
- Balandina Svetlana Yurevna
|
RU2763731C1 |
| THE USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-EN-4,7-DIONES AS AGENTS WITH ANTIMICROBIAL ACTIVITY AGAINST S. AUREUS |
2022 |
- Maslivets Andrei Nikolaevich
- Tretiakov Nikita Alekseevich
- Balandina Svetlana Iurevna
|
RU2790379C1 |
