FIELD: organic chemistry; pharmaceuticals.
SUBSTANCE: invention relates to the use of compounds of the class (Z)-9-aroyl-8-hydroxy-6-(2-hydroxyphenyl)-2-(((E)-pyridin-3-ylmethylene)hydrazono)-1-thia-3,6-diazospiro[4.4]non-8-ene-4,7-diones of the following formula
,
where R=H (a), CH3 (b), as an anti-tuberculosis agent.
EFFECT: invention provides a pronounced anti-tuberculosis effect.
1 cl, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| (Z)-9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-2-(((Z)-2-OXOINDOLIN-3-YLIDENE)HYDRAZONO)-1-THIA-3,6-DIAZASPIRO[4.4 ]NON-8-EN-4,7-DIONES WITH ANTIMICROBIAL ACTIVITY |
2021 |
- Mashevskaya Irina Vladimirovna
- Dmitriev Maksim Viktorovich
- Balandina Svetlana Yurevna
- Lukmanova Dzhamilya Nailevna
|
RU2763739C1 |
| ANTIOXIDANT BASED ON 2-[(R-BENZYLIDENE)HYDRAZONO]-8-HYDROXY-6-(2-HYDROXYPHENYL)-9-(4-BROMBENZOYL)-1-THIA-3,6-DIAZASPIRO[4.4]NONA-8-EN-4,7-DIONES |
2023 |
- Lukmanova Dzhamilia Nailevna
- Mashevskaia Irina Vladimirovna
- Dmitriev Maksim Viktorovich
|
RU2806329C1 |
| APPLICATION OF 2-[(R-BENZYLIDENE)HYDRAZONO]-8-HYDROXY-6-(2-HYDROXYPHENYL)-9-AROYL-1-THIA-3,6-DIAZASPIRO[4.4]NONA-8-EN-4,7-DIONES AS AGENTS WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Mashevskaia Irina Vladimirovna
- Lukmanova Dzhamilia Nailevna
- Apushkin Danila Iurevich
- Utushkina Taisiia Andreevna
- Iakushina Karolina Evgenevna
- Andreev Aleksandr Igorevich
|
RU2783241C1 |
| ANTITUBERCULOSIS AGENT BASED ON 4'-HYDROXY-1'-(2-HYDROXYPHENYL)-3'-ACYL-SPIRO[BENZO[b][1,4]THIAZINE-2,2'-PYRROLE]-3,5'(1 'H,4H)-DIONES |
2023 |
- Balandina Svetlana Iurevna
- Lukmanova Dzhamilia Nailevna
- Mashevskaia Irina Vladimirovna
|
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| USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYETHYL)-1,3,6-TRIAZASPIRO[4,4]NON-8-EN-2,4,7-TRIONES AS ANTITUBERCULOUS AGENTS |
2023 |
- Maslivets Andrei Nikolaevich
- Tretiakov Nikita Alekseevich
- Balandina Svetlana Iurevna
|
RU2798423C1 |
| APPLICATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-1,3-DIALKYL-2-THIOXO-1,3,6-TRIAZASPIRO[4.4 NON-8-ENE-4,7-DIONES AS AGENTS WITH ANTIMICROBIAL ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Tretyakov Nikita Alekseevich
- Balandina Svetlana Yurevna
|
RU2763731C1 |
| METHOD FOR PREPARATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-2-PHENYL-1-THIA-3,6-DIAZASPIRO[4,4]NON-2,8-DIENE-4,7-DIONES |
2016 |
- Stepanova Ekaterina Evgenevna
- Maslivets Andrej Nikolaevich
- Kobelev Aleksandr Ivanovich
- Balandina Svetlana Yurevna
|
RU2631432C1 |
| METHOD OF PRODUCING 2-AMINO-9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-1-THIA-3,6-DIAZASPIRO[4.4]NONA-2,8-DIENE-4,7-DIONE |
2019 |
- Maslivets Andrej Nikolaevich
- Kobelev Aleksandr Ivanovich
- Stepanova Ekaterina Evgenevna
- Balandina Svetlana Yurevna
|
RU2707195C1 |
| APPLICATION OF 8-HYDROXY-6-(2-HYDROXYETHYL)-9-(4-METHYLBENZOYL)-2-PHENYL-1-THIA-3,6-DIAZASPIRO[4.4]NON-2,8-DIENE-4,7-DIONE AS AN AGENT WITH ANTIMICROBIAL ACTIVITY AGAINST THE S. AUREUS CULTURE |
2023 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2803888C1 |
| USE OF 9-BENZOYL-8-HYDROXY-6-(2-HYDROXYETHYL)-2-PHENYL-1-THIA-3,6-DIAZASPIRO[4.4]NONE-2,8-DIEN-4,7-DIONE AS AN ANTIFUNGAL DRUG |
2022 |
- Maslivets Andrei Nikolaevich
- Tretiakov Nikita Alekseevich
- Balandina Svetlana Iurevna
|
RU2791043C1 |
