FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, specifically to a pharmaceutical composition containing neoantigen peptide for use in the treatment of mammary gland cancer. The obtained pharmaceutical composition contains neoantigen peptide containing tumor-specific neoepitope containing one or several adjacent mutant amino acids encoded by a sequence obtained by a mutation of a reading frame shift in GATA3 gene, where tumor-specific neoepitope is encoded by GATA3 gene of subject’s cancer cells or expressed by subject’s cancer cells.
EFFECT: invention can be used for the effective treatment of mammary gland cancer.
23 cl, 9 dwg, 3 tbl, 9 ex
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Authors
Dates
2022-06-01—Published
2017-03-31—Filed