NEOANTIGENS AND THEIR APPLICATION METHODS Russian patent published in 2022 - IPC C07K14/47 C07K16/30 A61K38/17 A61K39/00 A61P35/00 

Abstract RU 2773273 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, specifically to a pharmaceutical composition containing neoantigen peptide for use in the treatment of mammary gland cancer. The obtained pharmaceutical composition contains neoantigen peptide containing tumor-specific neoepitope containing one or several adjacent mutant amino acids encoded by a sequence obtained by a mutation of a reading frame shift in GATA3 gene, where tumor-specific neoepitope is encoded by GATA3 gene of subject’s cancer cells or expressed by subject’s cancer cells.

EFFECT: invention can be used for the effective treatment of mammary gland cancer.

23 cl, 9 dwg, 3 tbl, 9 ex

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RU 2 773 273 C2

Authors

Runi, Majkl Stiven

Dates

2022-06-01Published

2017-03-31Filed