METHODS FOR TREATMENT USING JAK INHIBITOR COMPOUND Russian patent published in 2022 - IPC A61K31/4545 A61P11/00 A61P27/02 

FIELD: medicine; ophthalmology.

SUBSTANCE: group of inventions relates to the field of medicine, namely ophthalmology; it is intended for the treatment of an inflammatory eye disease in a mammal. A method for the treatment of an inflammatory eye disease in a mammal includes the injection of a pharmaceutical composition, including 5-ethyl-2-fluoro-4-(3-(5-(1-methylpiperidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-2-yl)-1H-indazol-6-yl)phenol or its pharmaceutically acceptable salt and a pharmaceutically acceptable carrier, into the mammalian eye. The use of 5-ethyl-2-fluoro-4-(3-(5-(1-methylpiperidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-2-yl)-1H-indazol-6-yl)phenol or its pharmaceutically acceptable salt for the treatment of an inflammatory eye disease in a mammal is also provided. In addition, a method for the treatment of a respiratory disease in a mammal is presented, including the injection of a pharmaceutical composition to a mammal, including 5-ethyl-2-fluoro-4-(3-(5-(1-methylpiperidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-2-yl)-1H-indazol-6-yl)phenol or its pharmaceutically acceptable salt and a pharmaceutically acceptable carrier, where the respiratory disease is a pulmonary infection, helminthiasis, pulmonary arterial hypertension, sarcoidosis, lymphangioleiomyomatosis, bronchiectasis or infiltrative pulmonary disease, etc.

EFFECT: use of the group of inventions makes it possible to increase the efficiency of the treatment of inflammatory and infectious-inflammatory diseases.

25 cl, 2 tbl, 2 ex