IMIDAZOPYRIDAZINE COMPOUND Russian patent published in 2022 - IPC C07D487/22 A61K31/5025 A61K31/519 A61P35/00

Abstract RU 2765099 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to an imidazopyridazine compound by the chemical Formula 1, wherein, in the chemical Formula 1: R₁ represents halogen, L represents -CH=CH-, R₂ represents -O-(CH₂)n-, n is an integer from 1 to 3, W represents a saturated 6-membered unsubstituted or substituted with a hydroxy group monocyclic heterocycloalkyl containing 1 N atom, and R₃ represents H or hydroxy. Also proposed is a pharmaceutical composition exhibiting inhibitory activity against the growth of SK-CO-1 cell, containing a compound by the chemical Formula 1 as an active ingredient.

EFFECT: proposed imidazopyridazine compound has a high inhibitory activity against cell growth and, thus, can be successfully applied as a preventive or therapeutic agent against cancer or a tumour.

Chemical Formula 1

5 cl, 1 tbl, 2 ex

Similar patents RU2765099C2

Title	Year	Author	Number
METHOD FOR PREPARING DIHYDROINDENAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND USING THEM AS PROTEIN KINASE INHIBITOR	2009	Jan Sjujtsin Sjueh Lun Lo Tszjuan'	RU2528408C2
N-7 SUBSTITUTED PURINES AND PYRAZOLOPYRIMIDINES, COMPOSITIONS THEREOF AND METHODS FOR USE	2010	Li Vendi Lissikatos Dzhozef P. Pehj Chzhunkhua Robardzh Kirk D.	RU2515541C2
NOVEL COMPOUND OF 2,3,5-SUBSTITUTED THIOPHENE AS A PROTEIN KINASE INHIBITOR	2017	Sim Tae Bo Hur Woo Young Song Chi Man Yoon Ho Jong Choi Seung Hye Cho Han Na Choi Hwan Geun Kim Nam Doo Son Jung Beom Ko Eun Hwa Kim Hyun Kyoung Cho Joong Heui Kang Seock Yong Kim So Young Ko Yi Kyung Lee Seung Yeon Yoon Suk Kyoon Bae Jae Hyun	RU2724957C2
COMPOUND BASED ON DIHYDRONAPTHYRIDINONE, METHOD OF ITS OBTAINING, AND ITS USE IN MEDICINE	2021	Zhou, Fusheng Xu, Xiaoming Zhang, Leitao Li, Xin Tang, Lili Lan, Jiong	RU2809869C1
IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES	2009	Uill'Jams Brajan Dzhon Berdini Valerio Karr Marija Gratsija Kongriv Majlz Stjuart Frederikson Martin Griffits-Dzhounz Sharlott Mehri Khamlett Kristofer Charl'Z Frederik Mehdin Ehndrju Mjurrej Kristofer Uill'Jam Benning Radzhip Kaur Saksti Gordon Vikerstaff Ehmma Vudkhehd Ehndrju Dzhejms Vudkhehd Stiven Dzhon Frejn Ehddi Zhan Ehdgar Govarts Tom Kornelis Khortense Anzhibo Patrik Rene	RU2518089C2
IMIDAZO[1,2-b]PYRIDAZINE AND PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AND USE THEREOF AS PROTEIN KINASE INHIBITOR	2007	Birss Dehvid Dzh. Lju Sjao-Khoj Vankajalapati Khariprasad Sjuj Jun	RU2487875C2
THIENO[3,2-d]PYRIMIDINE DERIVATIVES, POSSESSING INHIBITING ACTION WITH RESPECT TO PROTEINKINASE	2011	Son Dzung Beom Dzung Seung Khiun Choj Va Il Dzung Joung Khee Choj Dzae Jul Song Dzi Jeon Li Kiu Khang Li Dzae Chul Kim Eun Joung Akhn Jung Gil Kim Maeng Sup Choj Khvan Geun Sim Tae Bo Kham Joung Dzin Park Dong-Sik Kim Khvan Kim Dong-Vook	RU2524210C2
NEW COMPOUND AS A PROTEIN KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND	2019	Park Ji-Yeon Kim Seung Chan Ki So Young Shim Ye-Ri	RU2785734C1
DERIVATIVES OF BENZIMIDAZOL, COMPOSITIONS CONTAINING THEM, OBTAINING AND APPLICATION	2004	Liu Ziping Pazhe Daniel' Uolpol Kristofer Jang Khua	RU2346938C2
NEW QUINOLINE COMPOUNDS	2018	Go, Khajbin Van, Chzhao-Kuj Tsin, Lokhen Lyu, Tsyan Cheun, Ving Shun	RU2810113C2

RU 2 765 099 C2

Authors

Kham, Eun Dzhin

Kan, Sok Dzhon

Dates

2022-01-25—Published

2018-01-23—Filed